2025-12-24
Mesitylene, chemically known as 1,3,5-trimethylbenzene, is an aromatic hydrocarbon widely utilized in chemical synthesis, specialty solvents, and advanced material processing. This article provides a comprehensive overview of mesitylene, focusing on its physicochemical parameters, industrial usage pathways, safety considerations, and evolving market context.
Mesitylene is a clear, colorless aromatic liquid classified under alkylbenzenes. Its molecular structure consists of a benzene ring substituted with three methyl groups at the 1, 3, and 5 positions, resulting in high symmetry and distinct steric characteristics. This structure directly affects its chemical stability, solubility behavior, and reactivity profile.
In industrial contexts, mesitylene is primarily valued as an intermediate and solvent rather than a consumer-facing chemical. It serves as a building block in fine chemicals, agrochemical intermediates, and specialty resins. The central theme of this article is to explain how mesitylene’s intrinsic properties translate into functional roles across multiple value chains.
Understanding mesitylene’s technical parameters is critical for correct material selection, safe handling, and formulation compatibility. The following table summarizes standard industrial-grade specifications commonly referenced in global trade and production.
| Parameter | Specification |
|---|---|
| Chemical Name | 1,3,5-Trimethylbenzene |
| CAS Number | 108-67-8 |
| Molecular Formula | C9H12 |
| Molecular Weight | 120.19 g/mol |
| Appearance | Clear, colorless liquid |
| Boiling Point | 164–165°C |
| Melting Point | -44°C |
| Density (20°C) | Approx. 0.865 g/cm³ |
| Solubility | Insoluble in water; miscible with organic solvents |
These parameters determine how mesitylene behaves during reactions, storage, and transportation. Its relatively high boiling point and low water solubility make it suitable for high-temperature processes and moisture-sensitive formulations.
Mesitylene’s industrial relevance spans several interconnected sectors. Each application is driven by a combination of structural stability, solvent compatibility, and controlled reactivity.
In organic synthesis, mesitylene functions as both a solvent and a reactant. Its sterically hindered aromatic ring is often used to stabilize reactive intermediates, particularly in Friedel–Crafts reactions and catalytic studies. Research laboratories and fine chemical producers rely on mesitylene for reproducible reaction environments.
Mesitylene is used as a precursor in the production of mesityl oxide and other downstream derivatives. These derivatives play roles in resins, coatings, and polymer modifiers. Its controlled volatility and aromatic nature contribute to consistent processing behavior during material formulation.
As a solvent, mesitylene is favored in niche applications where non-polarity and thermal stability are required. It is commonly used in electronics-related chemistry, catalyst preparation, and analytical calibration where solvent purity directly affects output reliability.
Q1: How does mesitylene differ from other trimethylbenzene isomers?
Mesitylene differs due to the symmetrical placement of its three methyl groups, which reduces ring reactivity compared to other isomers. This steric hindrance results in greater chemical stability and predictable reaction pathways.
Q2: How should mesitylene be stored to maintain stability?
Mesitylene should be stored in tightly sealed containers made of compatible materials, away from heat sources and oxidizing agents. Industrial storage typically follows flammable liquid regulations, with temperature control and adequate ventilation.
Q3: How is mesitylene handled in terms of safety and compliance?
Handling mesitylene requires standard aromatic hydrocarbon precautions, including the use of personal protective equipment and compliance with regional chemical safety standards. Safety data sheets provide guidance on exposure limits and emergency measures.
Global demand for mesitylene is closely tied to downstream chemical manufacturing and research activity. Growth in specialty chemicals, electronic materials, and advanced polymers continues to support stable demand. Market participants increasingly emphasize supply consistency, analytical documentation, and regulatory alignment.
In mature markets, procurement decisions are often influenced by supplier reliability and specification transparency rather than volume alone. This trend reinforces the importance of technical communication and quality assurance in mesitylene distribution.
AECOCHEM provides mesitylene solutions tailored to the requirements of industrial and research-oriented clients. By aligning product specifications with international standards and maintaining stable supply channels, AECOCHEM supports consistent application performance across diverse use cases.
Organizations seeking detailed specifications, regulatory documentation, or sourcing consultation are encouraged to contact AECOCHEM directly. A dedicated technical and commercial team is available to discuss application needs and supply arrangements.